Pioneering Macrophage-Subset Targeting for Transformative TherapiesSpica Therapeutics is a pioneering biotech company dedicated to transforming macrophage biology into breakthrough therapies for patients across multiple therapeutic areas. Leveraging its proprietary functional macrophage fingerprinting technology, Spica identifies and selectively targets disease-relevant macrophage subsets to address unmet medical needs in oncology, fibroinflammatory and autoimmune diseases.Founded on groundbreaking research conducted at the University of Aarhus, Southern Denmark University and INSERM, Spica operates from its headquarters in Belgium, with an additional site in Denmark . Powered by Bioqube Ventures’ venture creation model, the company is developing a robust pipeline of innovative therapies designed to modulate macrophages and improve patient outcomes. Spica Therapeutics is now advancing two lead programs with the goal of delivering life-changing therapies.

Our Innovation

  • Proprietary Platform: Functional macrophage fingerprinting technology to identify and target pathogenic macrophage subsets.

  • Therapeutic Areas: Advancing two lead programs focused in oncology and fibroinflammatory diseases.

  • Scientific Foundations: Built on groundbreaking research published in highly ranked journals, including a recent Nature Communications publication.

Leadership

  • James Rush PhD, CEO

  • Jim Van heusden PhD, Independent Chairman

  • Anders Etzerodt PhD, CSO & Co-founder

  • Geert Tackaert MEc, Finance Director

  • Hilde Revets PhD, Director Non-clinical Development

  • Jonas H. Graversen PhD, Danish Site Head & Co-founder

  • Supported by Bioqube Ventures’ proven venture creation model. LinkedIn or website Bioqube

Scientific Co-founders

  • Prof. Toby Lawrence, Co-founder

  • Prof. Holger J. Møller, Co-founder

  • Prof. Søren K. Moestrup, Co-founder

News & Events

Press releases

Contact

Please contact us at [email protected]Headquartered in Belgium with operations in Denmark. Powered by Bioqube Ventures.Copyright © 2025 Spicatx. All rights reserved | Privacy Notice | Registered as a company in Belgium | VAT: BE1012800853